• 14.Experiments on Children by the U.S. Government and Government-Funded Research

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      1. Do your own research on the information provided and then come up with your own conclusions.

      2. This article contains many names and other information that can be researched.

      3. Trust your gut feeling on information provided as this post may contain slanted information.

      4. A very tragic and sad subject but it must be researched to stop experiment on children.

      American government agencies and government-funded institutions conducted or supported numerous experiments involving children during the twentieth century. Some exposed institutionalized children to radioactive substances, infectious diseases, psychedelic drugs, electroshock, or psychological manipulation.

      However, three categories must be kept separate:

      1. Experiments conclusively documented as part of CIA programs such as MKULTRA.

      2. Experiments financed or supported by other government agencies.

      3. Experiments conducted at public hospitals or institutions for which a direct CIA connection has been alleged but not proved.

      This distinction is especially important because CIA officials ordered most MKULTRA records destroyed in 1973.

      1. What MKULTRA actually was

      CIA Director Allen Dulles approved MKULTRA on April 13, 1953. The program sought chemical, psychological, biological, and behavioral techniques that might be useful for interrogation, incapacitation, influence, or manipulation.

      The surviving records show at least:

      • 149 subprojects
      • More than 80 participating institutions
      • 185 nongovernment researchers
      • Universities, hospitals, prisons, pharmaceutical
        companies, foundations, and research centers
      • Tests involving LSD and other drugs, hypnosis,
        sensory deprivation, sleep disruption, electroshock, psychological stress,
        and surreptitious drug administration

      Frequently, researchers received CIA money through intermediary foundations and did not disclose the true sponsor to their institutions or subjects. The CIA also gave LSD to some people without their knowledge.

      The 1977 Senate hearing found that testing was conducted upon people from different social groups, sometimes without informed consent. The Supreme Court later acknowledged that MKULTRA included experiments in which dangerous drugs such as LSD were secretly given to unwitting subjects. Read the 1977 Senate MKULTRA hearing and the Supreme Court’s account in CIA v. Sims.

      A congressional hearing published in 2026 revisited the surviving evidence, including the discovery of seven boxes of financial records that escaped destruction. Read the 2026 House hearing record.

      2. Were children experimented upon under MKULTRA?

      The most accurate answer is:

      Children unquestionably underwent LSD, electroshock, and other behavioral experiments during the MKULTRA era, but the surviving records do not establish that every such pediatric experiment was financed or controlled by the CIA.

      There are CIA Reading Room materials indexed under “Experiments with Children”, and some MKULTRA-supported institutions treated children. Nevertheless, the destroyed files make it impossible to reconstruct every subject, institution, and funding relationship.

      Claims that all of the following child experiments were “MKULTRA” therefore go beyond the available evidence.

      3. Lauretta Bender’s electroshock experiments on children

      Child psychiatrist Dr. Lauretta Bender conducted extremely controversial work at New York’s Bellevue Hospital and later at Creedmoor State Hospital.

      Electroconvulsive treatment

      Beginning in the 1940s, Bender administered electroconvulsive treatment, commonly called electroshock, to children diagnosed with what was then called “childhood schizophrenia.”

      Her published work reportedly included:

      • Children as young as approximately three or four
      • Repeated electroshock treatments
      • A systematic series involving 98 children
      • Some children receiving treatments daily
      • Comparisons of children’s behavior and drawings
        before and after shock
      • Use of other treatments, including insulin shock
        and Metrazol-induced convulsions

      Standards of diagnosis were considerably different at the time. Some children labeled schizophrenic would probably receive diagnoses involving autism, developmental disability, trauma, or other conditions today.

      Bender believed that shock might reorganize the children’s development and behavior. Critics argue that the children could not meaningfully consent, that parents may not have understood the risks, and that institutionalized children were unable to refuse.

      LSD experiments

      During the 1950s and 1960s, Bender and colleagues also administered LSD to hospitalized children diagnosed with autism or childhood schizophrenia.

      A published study described an initial group of 14 autistic children. Other accounts place participating children between approximately four and fifteen years old. Treatment sometimes involved repeated doses rather than a single exposure.

      Reported observations included:

      • Changes in speech and verbalization
      • Altered perceptions
      • Anxiety and agitation
      • Distorted colors, faces, and objects
      • Children complaining that they were being
        experimented upon
      • Researchers interpreting resistance as part of
        the child’s psychiatric condition

      Bender’s team published the research as attempted treatment, not simply as a covert interrogation study. The historical record confirms that LSD was administered to children, but it does not conclusively prove that Bender’s pediatric studies were an MKULTRA subproject. An academic history of these experiments is available through the NIH Bookshelf, and the researchers’ 1963 report can be read in this transcription of “LSD and UML Treatment of Hospitalized Disturbed Children”.

      4. Radioactive “science club” experiments at Fernald School

      One of the clearest federally supported cases involved the Walter E. Fernald State School in Massachusetts, an institution for children classified at the time as intellectually disabled.

      MIT investigators, working with Fernald officials, conducted nutritional research involving radioactive tracers:

      • In 1946, 17 boys received radioactive iron.
      • Between 1950 and 1953, 57 boys participated in
        experiments using radioactive calcium.
      • Some radioactive material was incorporated into
        food or drink so researchers could study mineral absorption.
      • The Atomic Energy Commission supported portions
        of the research.
      • Children were recruited into what was called a
        “science club.”
      • Participation brought privileges such as special
        meals, outings, attention, or baseball-related activities.

      Letters seeking parental permission described nutritional studies, blood tests, cereal, iron, and vitamins. At least one important letter did not disclose that radioactive material would be administered.

      The federal Advisory Committee on Human Radiation Experiments concluded that the doses were unlikely to have physically harmed the boys. Nevertheless, it found the studies morally troubling because:

      • Parents received incomplete or misleading
        information.
      • Institutionalized children were selected because
        they were convenient and vulnerable.
      • The children were encouraged with rewards that
        held unusual power in an institution.
      • The research offered little or no direct medical
        benefit to them.

      The committee concluded that wrongs had been committed against the Fernald children and recommended an apology. See the government’s Fernald School investigation and recommendation concerning the children.

      This was a federal radiation-research scandal, not a demonstrated CIA or MKULTRA operation.

      5. Other radioactive experiments involving children

      The Advisory Committee identified 81 pediatric radiation-research projects in government and medical records. It classified 37 as nontherapeutic and closely reviewed 21 that were conducted or funded by the federal government between 1944 and 1974.

      Examples included:

      Johns Hopkins thyroid experiment

      In 1953, investigators administered iodine-131 to:

      • 34 children, ages approximately two months to
        fifteen years, who had hypothyroidism
      • An unspecified number of healthy control children

      Researchers measured how much radioactive iodine the thyroid absorbed. The study helped investigators understand childhood thyroid disease, but the use of healthy children as controls raised ethical questions.

      University of Minnesota study

      In 1951:

      • Four children with nephrotic syndrome received an
        amino acid labeled with sulfur-35.
      • Two children hospitalized for unrelated
        conditions served as controls.

      The purpose was to study whether children with nephrotic syndrome had impaired protein production.

      Los Alamos thyroid study

      In 1963, eight healthy children received extremely small quantities of iodine-125 and iodine-131 to evaluate a method for measuring thyroid function.

      The radiation doses were reportedly very low, but the children received no therapeutic benefit. Questions remain about parental authorization and the fairness of selecting children for such research.

      These examples and the government’s risk analysis appear in Risk of Harm and Nontherapeutic Research with Children.

      6. Wrentham State School fallout experiment

      Children at the Wrentham State School in Massachusetts were involved in research related to radioactive fallout.

      Researchers studied how radioactive iodine was taken up by the thyroid. The children were institutionalized and therefore especially dependent upon officials deciding whether they would participate.

      The federal advisory committee found that both Fernald and Wrentham placed research burdens on disadvantaged children whose interests were not adequately protected. Its conclusion is available in the government’s chapter on research involving children.

      Again, this was radiation research connected to federal programs, not established MKULTRA activity.

      7. Willowbrook hepatitis experiments

      From approximately 1955 through the early 1970s, researchers studied hepatitis at Willowbrook State School on Staten Island, a crowded institution for children with intellectual disabilities.

      Some newly admitted children were deliberately exposed to hepatitis. In certain experiments, infectious material derived from the feces of people with hepatitis was placed in preparations given to children. Researchers then monitored:

      • Symptoms
      • Liver enlargement
      • Jaundice
      • Blood and liver-function changes
      • Differences between what became known as
        hepatitis A and hepatitis B
      • Possible protective effects of gamma globulin

      Researchers defended the studies by arguing that hepatitis was already extremely common at Willowbrook and that most newly admitted children would eventually become infected. They also maintained that controlled exposure could allow closer observation and possibly produce immunity.

      Those defenses remain deeply controversial because:

      • The subjects were children with intellectual
        disabilities.
      • They could not provide meaningful consent.
      • Admission to an overcrowded institution was
        sometimes connected with joining the hepatitis unit.
      • Parents may therefore have faced coercive
        circumstances.
      • Infection was deliberately induced for research.
      • The children carried the burdens while society
        received the scientific benefits.

      The research contributed to knowledge concerning different hepatitis viruses and prevention, but useful scientific results do not erase unethical subject selection or inadequate consent. See the Willowbrook bioethics case history and a medical history of hepatitis-virus discovery.

      Willowbrook was a New York state institution and the work involved public and academic medical authorities. It is not documented as MKULTRA.

      8. Federal pellagra research in orphanages

      In 1914, U.S. Public Health Service physician Joseph Goldberger investigated pellagra, a severe disease associated with poverty and malnutrition.

      At orphanages where pellagra was common, Goldberger changed children’s diets by adding foods such as:

      • Milk
      • Eggs
      • Meat
      • Vegetables
      • Legumes

      Pellagra declined dramatically, helping demonstrate that the disease resulted from nutritional deficiency rather than infection.

      This differs from many later scandals because the dietary intervention generally benefited the children. Nevertheless, it illustrates the long-standing government practice of using captive populations—orphans, prisoners, patients, and institutionalized people—as convenient research groups.

      The history is described by the University of Alabama at Birmingham and in a peer-reviewed historical analysis.

      9. Why institutionalized children were repeatedly selected

      The same pattern appears throughout this history. Researchers often selected children who were:

      • Orphans
      • In foster care
      • Intellectually or developmentally disabled
      • Confined in psychiatric hospitals
      • Living in state institutions
      • Poor or members of racial minorities
      • Unable to communicate effectively
      • Dependent upon officials for food, privileges,
        treatment, or admission

      Such children were convenient because researchers could control their schedules, diets, medication, and environment. They were also less likely to have parents with the power or resources to challenge prestigious doctors and government institutions.

      The federal radiation committee emphasized that convenience did not justify imposing research burdens upon children who were already disadvantaged.

      10. What is proven—and what remains unproven

      11. Why the complete story may never be known

      In January 1973, outgoing CIA Director Richard Helms ordered MKULTRA files destroyed. The principal surviving collection consisted largely of financial records that had been stored separately and discovered in 1977.

      Consequently:

      • Complete subject lists do not exist.
      • Some institutions cannot be definitively
        connected to individual experiments.
      • Victims may never have learned what was done to
        them.
      • Researchers sometimes did not know the CIA was
        the ultimate sponsor.
      • Legitimate suspicions cannot always be proved.
      • Unsupported stories can also become mixed with
        documented history.

      The responsible conclusion is neither “nothing happened” nor “every allegation is true.” The record proves extensive abuses while also containing large and deliberate gaps.

      12. Reforms produced by these scandals

      Public exposure of human experimentation helped bring about:

      • Institutional Review Boards
      • Stronger informed-consent requirements
      • Special protections for children, prisoners, and
        institutionalized people
      • The National Research Act of 1974
      • The National Commission for the Protection of
        Human Subjects
      • The 1979 Belmont Report
      • Federal regulations known collectively as the
        Common Rule

      The Belmont Report established three central principles:

      • Respect for persons: participation must be voluntary and based on
        understandable information.
      • Beneficence: risks must be minimized and reasonable in relation to potential
        benefits.
      • Justice:
        vulnerable populations must not be selected simply because they are easy
        to control.

      The government’s official history is available through the HHS Belmont Report and Common Rule information.

      The historical record therefore supports a grave conclusion: American government agencies and government-supported researchers repeatedly failed to protect vulnerable children. The strongest account is made by presenting those documented facts plainly, while clearly labeling CIA connections that remain allegations rather than proven history.